Services

Online inquiry

  •  

Contact us

Alpaca Antibody Library Construction by Phage Display

Alpaca Antibody Library Construction by Phage Display

Alpaca antibodies only have heavy chains without light chains, so they are called heavy-chain antibodies (hcAb). Alpaca antibodies lack light chains and are composed of 4 HCs and 2 VHs. The VH region is also called nanoantibody or single domain antibody (sdAb). The independent alpaca VH region has the complete antigen-binding capacity. Compared with artificially modified single-chain Fv (scFv), it is easy to aggregate. Alpaca antibodies have stable properties, such as maintaining activity at 60 ℃ and resisting extreme pH environments. Creative Biolabs has been committed to antibody preparation research for many years. We have experienced antibody preparation technicians, and have accumulated sufficient experience in antibody customization and recombinant protein production. Based on phage antibody display technology, we can provide customers with antibody production from rabbit, mouse, camel, sheep, chicken, and shark sources.

Our Services

Creative Biolabs has a natural library of nearly 100 billion levels, which can provide rapid screening services for alpaca antibody library, and complete the rapid screening of specific antibodies against various target proteins within 2-3 weeks.

  • Antigen design of alpaca antibody phage display library
  • Animal immunization of alpaca antibody phage display library
  • Library construction and screening of alpaca antibody phage display library

Key Features of Alpaca Antibodies

  • It has a longer CDR3 region and has a stronger ability to specifically bind to the antigen
  • Simple structure, easy to genetic engineering modification
  • The preparation is simple, and it is easy for industrialized scale-up production
  • Easy to humanize

Workflow

Workflow of alpaca antibody phage display library construction service

Our Advantages

  • Rich samples: derived from more than 100 different kinds of camel samples: alpaca, camel, llama, providing higher antibody diversity
  • Large storage capacity: the total storage capacity is nearly 10*pfu, which will be optimized to over 100 billion in the future.
  • Ultra-high quality: 100% insertion accuracy rate, 97% sequence accuracy rate, 200 clones were randomly selected for sequencing, all without repetitive sequences.

Creative Biolabs can meet the needs of customers for providing phage display library construction services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).

Biophage Technology

Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.

Contact Us
  • Global Locations
Privacy Policy | Cookie Policy | Copyright © 2024 Creative Biolabs. All rights reserved.