After encountering an antigen, the host humoral immunity activates and triggers the production of antibodies against foreign protein epitopes. The binding region is called an epitope. Knowledge of epitopes is valuable for the development of effective antibody reagents for research and therapy. Understanding these protein epitopes is essential for understanding the pathogenesis of pathogen infection and developing diagnostic reagents, therapeutic antibodies, and effective vaccines. Peptide phage display libraries are useful tools for identifying continuous or linear epitopes involved in the interaction with antibodies. Isolation and identification of mimotopes from peptide phage libraries is an effective method for improving immunological research to design and develop candidate vaccines. In addition, epitope mapping has an important role in vaccine development because it can help clarify the immune response. Therefore, the knowledge of epitope mapping allows the construction of peptide vaccines based on epitope specificity.
Epitope mapping is a method commonly used to identify antibody antigen-binding sites. However, epitope mapping can also be used for other high-affinity protein interactions, including interactions with proteins, chemicals, and DNA. Creative Biolabs' phage-based epitope mapping service uses different types of phage, thus avoiding many steps and time required by traditional methods, which involve the recombinant cloning, expression and purification of different regions of the target gene.
Creative Biolabs can meet the needs of customers by providing epitope mapping services on time and on budget. We have in-depth knowledge and experience of the tools and processes involved in the phage projects. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
