Phage display technology links exogenous protein genes, such as antibody fragments, polypeptide fragments, and other cDNAs to gene VIII or gene III of phage surface structural protein using co-expression methods for in vitro display and expression. The antibody phage display library has always been a powerful tool for the development of fully human therapeutic antibodies. We have built a mature phage antibody display library construction platform, which can provide customers with different levels and types of antibody phage display libraries. Our research team has a wealth of knowledge and years of experience and can construct a large-capacity phage display library in a short time. Creative Biolabs provides one-stop scientific research services based on phage display technology, including the construction and screening of phage antibody libraries, antibody humanization, and the production of specific monoclonal antibodies.
Creative Biolabs has M13, T4 and T7 phage display systems. According to the customer's project requirements (the size of the displayed protein or antibody fragments and other parameters), different phages will be used for protein or antibody display. Our services are listed as follows, but are not limited to:
In the completed cases, the M13 phage pIII gene display system is more commonly used, and the constructed library capacity can reach 1011, of which the effective library capacity is 109. At the same time, customers can also provide antigens to obtain monoclonal antibodies with higher affinity and specificity. Usually, the affinity of antibodies prepared based on this method can reach 10-13 M level.
Creative Biolabs can meet the needs of customers for providing phage display library construction services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
