Pests are those species that attack certain resources we humans want to protect, and succeed enough in being economically important or just a major annoyance. Trees and woody plants, for example, maybe attacked individually by many pests and pathogens or infected by multiple microorganisms. In particular, infections caused by tree-specific bacterial pathogens have become more common over the past decade. Phages are an important part of the plant microbiome and are increasingly used in plant-pathogen control due to their highly specific host range and ability to selectively kill only target pathogens. Creative Biolabs has a range of biocontrol technologies that can be used for such purposes, including phage therapy, and genetically modified insect approaches, and so on. Biological control is the use of living organisms to suppress pest populations, making them less destructive than otherwise. Biological control can be used to control all types of pests, including vertebrates, plant pathogens, weeds, and insects, but the methods and agents used vary for each pest.
Fig 1. Potential application approaches for the use of phage to treat bacterial diseases of trees. (Grace E R， et al., 2021) Bacteriophages are viruses that infect and replicate only within their specific host bacteria. Most phages isolated for biocontrol purposes belong to the order Caurovirinae. All members of the Caudovirales commonly used by our group have a genome with double-stranded DNA packaged into an icosahedral capsid, and a tail structure that binds to the bacterial host cell.
The insect microbiome is a rich resource that can be explored to control insect reproduction and insect populations. Creative Biolabs has a range of technologies available for such purposes, including phage therapy, genome editing technologies, and transgenic insect methods to provide professional consulting.
We specifically focused on various bacterial diseases of trees that are relevant to the existing phage biocontrol literature. Since several diseases are confined to the vasculature of the trunk and extremities, phages are particularly attractive targets for systemic delivery by injection or spray, potentially ensuring efficient dispersion throughout the tree vasculature.
Creative Biolabs can meet the needs of customers by providing pest control by phage solutions on time and on budget. We have in-depth knowledge and experience of the tools and processes involved in the phage projects. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
