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Phage-based Inorganic Materials

By mimicking the process of biomineralization in nature, phages and their peptides discovered from phage display can also be used in the synthesis of inorganic materials. In nature, specific binding proteins to various inorganic crystals, such as silicon dioxide in diatoms, iron oxide in magnetic bacteria, calcium carbonate in abalone shells, or calcium phosphate in bones and teeth, are found in organic-inorganic They play a key role in the synthesis of hybrid materials. Similarly, specific recognition peptides for desired crystal surfaces identified by phage display can be utilized to template the growth of various target inorganic crystals. Due to their monodisperse and elongated rod shape, many filamentous bacteriophages have been extensively studied as liquid crystal model systems. By varying variables such as concentration, ionic strength, and external field, phages are able to form ordered liquid crystal structures. In the low concentration range (below 5 mg/ml), the phages are randomly arranged in the isotropic liquid crystal phase. Some viral particles such as the M13 virus have been studied as solid-phase two-dimensional films and one-dimensional fibers at higher concentrations (10-20 mg/ml).

Fig 1. Schematic diagram of the M13 bacteriophage in a various liquid crystalline ordered structures and their microscopy image.Fig 1. Schematic diagram of the M13 bacteriophage in a various liquid crystalline ordered structures and their microscopy image. (Chung W J, et al.,2011)

Our Solutions

Our experience in all aspects of production and commitment to quality make our customized phage-based inorganic materials design and synthesis solutions a successful tool for scientists worldwide. All our inorganic materials come with a complete quality control package, including HPLC analysis to ensure purity and mass spectrometry analysis to confirm identity. Our solutions are listed as follows, but are not limited to:

  • Phages-based inorganic materials design
  • Phages-based inorganic materials synthesis
  • Phages-based inorganic materials purification
  • Phages-based inorganic materials identification
  • For crude products, MS analysis is optional
  • Any additional analysis

Our Analysis Methods

Elemental Analysis Molecular and Solid-State Analysis
Atomic absorption spectroscopy Nuclear magnetic resonance (NMR)
Auger electron spectroscopy (AES) Electron diffraction
Electron probe microanalysis (EPMA) Electron spin resonance (ESR)
Energy dispersive spectroscopy (EDS) Infrared spectroscopy (IR)
Electron spectroscopy for chemical analysis (ESCA) Mass spectrometry

Our Advantages

Phages-based Inorganic Materials
  • Solving problems with professional knowledge and creativity
  • Complex biological data interpretation
  • Responsive project management
  • Broad expertise in inorganic materials design and synthesis
  • We have rich experience in patent strategy
  • We provide inorganic materials with a detailed product certificate containing all analytical data, MS, NMR and other reports documents

Creative Biolabs can meet the needs of customers by providing solutions of phage-based inorganic materials development on time and on budget. We have in-depth knowledge and experience of the tools and processes involved in the phage projects. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for your project. If necessary, please feel free to contact us.

Reference

  • Chung W J, Sena M, Merzlyak A, et al. Phages as tools for functional nanomaterials development[J]. Comprehensive Biomaterials, Elsevier, Oxford, 2011: 95-111.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).

Biophage Technology

Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.

Contact Us
  • 1-631-416-1478
  • SUITE 203, 17 Ramsey Road, Shirley, NY 11967, USA
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