Phages are the most numerous organisms in the biosphere, and they are a ubiquitous feature of prokaryotes. Phage is a virus that infects bacteria. Phages, as tools for understanding basic molecular biology, vectors for horizontal gene transfer, driving forces for bacterial evolution, sources of diagnostic and genetic tools, and new therapeutic agents, have always been the focus of attention of scientists. Unraveling the biological characteristics of phages and their relationship with the host is the key to understanding microbial systems and their uses. Phages have various possible life cycles, and their interaction with the physical environment determines their role in bacterial/archaeological biology. Phage DNA characterization is an important method to study the biological characteristics of phages and their relationship with the host. Creative Biolabs provides phage DNA characterization services. Creative Biolabs' phage laboratory receives customer samples contaminated with unknown phage every day, so our team is quite experienced in phage DNA characterization.
We will define the host range of the phage, find its preferred breeding conditions, determine the allowable conditions (temperature, pH) for its survival, and test its sensitivity to factors such as disinfectants or drying. We provide phage genome sequencing services and can use electron microscopes to reliably identify and classify any phage based on its genome sequence and morphology. No matter what questions you have about phage, Creative Biolabs can answer.
Our team uses gel electrophoresis to separate DNA fragments in restriction digests and visualize the genetic fingerprints of Phages. Photos of phage genetic fingerprints contain valuable information about the phage and can be used for characterization and comparison purposes.
Our phage characterization service through whole-genome sequencing uses high-throughput sequencing to obtain the annotated genome of your phage. Phage DNA is purified using a specific DNA isolation protocol, and the remaining bacterial DNA contamination is removed by bioinformatics after sequencing.
Creative Biolabs' phage production and characterization services are different from the other phage companies lie in its extensive and in-depth knowledge, which is mainly based on original research by Creative Biolabs' scientists.
Creative Biolabs also have an in-depth understanding of the techniques and controls required for phage culture to avoid cross-contamination of phage and know how to obtain the highest number of phages in a single fermentation.
Creative Biolabs can meet the needs of customers for providing phage DNA characterization services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
