Phages are viruses that infect bacteria. It is estimated that phages are the most abundant organisms on earth, and there may be more than 10 31 individual phages on earth. The type of bacteria (strains or species) that the phage can infect is considered to be the host range of the phage in question. Host range is a key feature of phage therapy and general phage biology. Each phage has its own specific host range. It is generally accepted that most phages can only infect a small number of closely related bacteria. Although some phages can only infect one or a few bacterial strains, other phages can infect many species and even different genera of bacteria. Different methods of determining the host range may obtain different results, reflecting the multiple mechanisms by which bacteria resist phage infection, and reflecting the different infection steps that each method relies on. Creative Biolabs provides determination of phage host range services. Creative Biolabs' phage laboratory receives customer samples contaminated with unknown phage every day, so our team is quite experienced in phage research.
Fig 1. Subdivision of phages Based on Host Range.(de Jonge P A, et al., 2019)
With many years of experience in phage research, we are the best choice to provide custom phage testing services on time and on budget. Our services are listed as follows, but are not limited to:
Spot testing is a simple chemical procedure that uniquely identifies substances. It is easiest to test multiple phages at the same time; using a square plate, up to 36 phages can be detected at the same time. If you use a set of hosts that have been characterized using typed phages, you can use these typed phages as controls on each plate and ensure that the strains behave as expected.
The types including adsorptive, penetrative (transductive), bactericidal, productive, plaquing, spotting, and lysogenic.
The test sample can be from fermentation broth, air, sewage, soil, etc.
Creative Biolabs can meet the needs of customers for providing phage host-range determination services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
