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Phage Stability Test

Phages are the most abundant life form on earth. They can be found in all environments where bacteria grow: in the Sahara Desert, hot springs, North Sea, and polar inland waters. Phages were detected in groundwater and surface water, soil, food (such as sauerkraut, wine), sewage, and sludge. The ability of phages to survive under adverse conditions is highly diverse. Creative Biolabs provides phage stability testing services under different external physical and chemical factors, such as temperature, acidity, and ion conditions. This service is not only useful for those who are interested in the pharmaceutical and agricultural applications of phages, but also of great help to other people who use phages to understand the complex problem of phages' sensitivity to external factors. Various external physical and chemical factors, such as temperature, acidity, salinity, and ions, determine the occurrence, viability, and storage of phages, and they can damage the structural elements (head, tail, envelope), lipid loss, and DNA structure changes.

Our Services

Creative Biolabs can provide high-quality phage stability tests services. We provide different external physical and chemical factors to evaluate phage stability according to strict requirements. our services are listed as follows, but are not limited to:

  • Temperature
  • Temperature is a key factor in the survival rate of phages. It plays an important role in attachment, penetration, proliferation, and the length of the incubation period (in the case of lysogenic phages). Creative Biolabs provide different temperatures test, such as 30, 40, 45, 50, 55, 60, 65, 70, 80 ℃ and so on.

  • Acidity of the environment
  • Another important factor affecting the stability of phages is the acidity of the environment. Phagess can persist in an acidic environment. Creative Biolabs provide phage stability test service under different pH (1 - 11).

  • Salinity and ions
  • Osmotic shock has been shown to inactivate phages, and the persistence of phages in high-concentration NaCl or sucrose solutions is reduced. Creative Biolabs provides the stability of phage test incubated in salt solution at 37°C.

  • Phage morphology test and their persistence in extreme environments
  • Creative Biolabs provides phage stability test service under extreme environments.

Services Workflow

  • Phage preparation
  • Phage stability at a constant temperature, acidity of the environment or salinity and ions conditions
  • Preparation and visualization of processed phage
  • Perform transmission electron microscopy on the sample to observe the effect of different conditions on the morphology of the phage
  • Statistical analysis
Services Workflow

Our Service Features

All experiments will be performed in triplicate, and each sample was plated in duplicate. Our scientists use the SAS statistical software package to perform statistical analysis and analysis of variance with 95% confidence intervals.

Creative Biolabs can meet the needs of customers for providing phage stability testing services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).

Biophage Technology

Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.

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