As natural enemies of bacteria, phages have evolved to bind to their hosts with unparalleled specificity, and can quickly transmit and replicate their viral genomes. Fast and reliable detection of clinical samples, bacterial pathogen products in contaminated food, and water supply can significantly improve clinical outcomes and reduce the impact of socioeconomic diseases. But bacteriophages are the enemy of microbiological laboratories and bacterial industrial fermentation plants. In particular, mild bacteriophages will quietly infect the host bacteria, waiting for opportunities. In microbiology laboratories, strains contaminated with mild phages often appear new physiological and biochemical phenotypes, which affect the conclusions of experiments. In bacterial fermentation, the bacteria at the bottom plate used also face the problem of phage contamination. For example, when using beneficial bacteria to produce antibiotics, alcohol, acetic acid, acetone, and other products, if the beneficial bacteria contaminate the phage, the fermentation will fail, causing huge economic losses. Understanding the characteristics of bacteriophages, rapid detection, separation, and determination of titer play an important role in preventing bacteriophage contamination in production and scientific research.
Fig 1. Typical members of a few bacteriophage families. (Richter Ł, et al. 2018)
Phage is a type of virus that parasitizes microbial cells. We have processed many phage samples from soil, compost, feces, decaying organic matter, sewage, etc. Our services are listed as follows, but are not limited to:
The test sample can be fermentation broth, air, sewage, soil, etc. (As for the objects that cannot be sampled and need to be inspected, the surface can be wiped with cotton soaked in sterile water as the inspection sample). In order to facilitate separation, it can be proliferated and cultured first to increase the number of phages in the sample.
Creative Biolabs can meet the needs of customers by providing phage detection services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
