Phage Enrichment

Bacteriophages are the most abundant life form on earth. They play an important role in bacterial ecology, adaptation to new environments, and bacterial evolution and pathogenesis. Bacteriophages are very common in soil, and the direct counting method found that there are 10⁷-10⁹ phages per gram of soil. Phages are also very abundant in fresh water and seawater, which may be close to 10⁷ per milliliter. The global number is estimated to be 1031. However, certain phages are sometimes difficult to isolate directly, so enrichment procedures are usually required. Unfortunately, this technique will limit the diversity of isolated phages, because some enrichment schemes will cause bias because the phages that can reproduce most efficiently under experimental conditions dominate. Creative Biolabs provides customers with professional integrated phage enrichment, isolation, and data analysis services, aiming to help you to gain high purity phages from the environment.

Our Services

The goal of phage enrichment is to enrich your phages that can infect the desired host. This is done by removing endogenous bacteria from your sample and adding them to the bacterial culture medium and the growing culture of the host, and then incubating them. Our scientists with rich experiences can provide you with custom enrichment strategies. Our services are listed as follows, but are not limited to:

Other Related Services

• Phage enrichment from aqueous materials
• Phage enrichment from soil environments
• Phage project report

Workflow

During the project processing, Creative Biolabs' team will be monitoring each step to ensure you gain high purity phage.

• Environmental samples collection
• Phage sample processing
• Processing enrichment cultures
• Choice of isolation host(s) and enrichment culture variations
• Post-Infection processing

Phage Concentration Technologies

• Phage enrichment from aqueous materials using membrane filter adsorption and elution
• Phage enrichment from soil using bacillus as the model bacterium

The Advantages for Our Customers

• We will be your representative with phage isolation, from quoting to custom isolation service.
• Knowledge of your isolation, saving you time and money.
• Professionals analyze test data and effectively assist in solving technical problems.
• Our team is dedicated to meeting your needs as quickly as possible.
• Direct isolation combined with a plaque assay will be applied in the detection of phages

Creative Biolabs can meet the needs of customers by providing phage enrichment services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).