Creative Biolabs provides surface display library screening services to identify peptide ligands for various target molecules (such as enzymes, antibodies, cell surface receptors, or other biological products). The antibody library is screened for isolation, overexpression, and purification of monoclonal antibodies and subsequent preparation. the small number of phages displaying proteins that specifically bind to the target are recovered from a phage library, which usually has billions of unique displayed proteins. After several rounds of panning, the proteins displayed by the selected phage were identified by phage amplification and DNA sequencing. We provide biopanning after immobilizing the target molecule on a solid surface (bioassay plate), beads or solution, and then perform streptavidin-based capture.
Fig 1. Schematic representation of phage display library screening process. (Teixeira D, et al., 2018)
Phage display is a laboratory technique that uses phages to associate proteins with their respective genetic information to study protein-protein, protein-peptide, and protein-DNA interactions. Our scientists have applied this technology to display antibodies for therapeutic protein engineering. Our phage display service allows the selection ("panning") of recombinant antibody fragments from the antibody gene library and more convenient and more specific screening of individually selected antibody clones.
Creative Biolabs can meet the needs of customers for providing phage display library screening services on time and on budget. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for each professional for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
