Creative Biolabs is the world's leading CRO company, mainly focusing on the production of phages, and provides phage display services, and synthetic services of artificial phage genomes. Our mission is to innovatively manufacture the highest quality biomolecules and develop economic processes within an agreed time frame. The synthesis of artificial phage genomes is divided into four steps: design, construction, rescue, and testing. Design: Remove some non-essential genes, add genetic elements, or design the entire phage genome modularly, and split the designed genome sequence into Oligo sequences of about 100 nt that are conducive to synthesis; Construction: After synthesizing Oligo sequences, use a PCR machine to pass Anneal and Extend, assemble Oligo fragments into 1kb double strands, and assemble complete phage genomes by yeast recombination platform, PCR or Gibson; rescue: rescue into active phage particles using electroporation, cell-free expression systems or L-cell synthesis of artificial phage genomes; Test: Preliminary characterization of artificial phages by one-step growth and inhibition curves. Creative Biolabs is an independent contract manufacturing organization and contract research organization (CRO) and provide engineering synthetic phages design and production services for customers.
Creative Biolabs is the ideal outsourcing partner as we ensure that our clients have time to focus on their own areas of expertise, where Creative Biolabs is responsible for CMC (Chemistry, Manufacturing, and Controls) activities. Our services are listed as follows, but are not limited to:
The use of fluorescently labeled phages can facilitate the detection of phages in mammalian cells and tissues. Molecular imaging can be very useful for studying phages in living systems.
Tetracysteine tags constitute an invaluable tool for gaining a deeper understanding of the mechanistic processes that control phage-host interactions.
Creative Biolabs can meet the needs of customers by providing synthetic phages design and production services on time and on budget. We have in-depth knowledge and experience of the tools and processes involved in the phage projects. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for your project. If necessary, please feel free to contact us.
Please kindly note that our services can only be used to support research purposes (Not for clinical use).
Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.
