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Phage Display-Based Antibody Development Platform

Phage Display-Based Antibody Development PlatformPhage display technology was first described by Smith in 1985, and then further expanded by a team of scientists. This technology is mainly based on displaying the protein of interest on the surface using phage, and then it is used to query the constructed library containing millions or even billions of displayed phages. One of the successful applications of phage display technology is using large-capacity phage antibody libraries to isolate monoclonal antibodies. With our established mature antibody production platform, we can provide high-quality phage display library construction and customized phage display library screening services to meet the various needs of customers. Creative Biolabs now provides monoclonal antibody and recombinant antibody production services for humans, mice, rabbits, chickens, sheep, geese, pigs, cattle, horses, donkeys, camels, alpacas, etc. on the platform. We have extensive experience in library construction and screening, antibody humanization, antibody affinity maturation, production of specific monoclonal antibodies, and more services using phage display technology.

The Advantages of Phage Display-Based Antibody Development Platform

  • Our team can express full-length antibodies of various subtypes (IgG1, IgG2a, IgG2b, IgG3, IgG4, IgM, etc.), chimeric antibodies (human-mouse chimera, pika chimera, etc.), and antibody fragments (Fab, scFv) at the platform.
  • Creative Biolabs provides customized high-purity, high-concentration, and low-endotoxin antibodies according to customer requirements.
  • From shake flasks to bioreactors of different scales, there is no rest 24 hours a day, 7 days a week, to ensure rapid production.
  • Creative Biolabs can provide product features for instant transfection and develop stable expression cell lines to meet the needs of different customers.

Services Based on Phage Display-Based Antibody Development Platform

Phage Display-Based Antibody Development Platform

Antibody phage display is based on the genetic engineering of bacteriophages and repeated rounds of antigen-guided selection and phage propagation.

  • immune library construction service
  • Immune phage display library constructed from camel, alpaca, llama, or shark can generate VHH or VNAR with high affinity and specificity.

  • Naïve library construction service
  • The construction of the naïve library may increase the affinity of the final antibody to the target protein. Creative Biolabs can generate high-diversity antibody libraries for phage display, providing the most sophisticated binding agent for your project.

  • Semi-synthetic library construction service
  • We use phage as vectors to produce high-affinity custom semi-synthetic antibody libraries, with industry-leading titer assurance and quality assurance.

  • Synthetic library construction service
  • Creative Biolabs uses the M13 single-chain filamentous phage display system to co-express recombinant proteins or antibodies with phage pIII protein.

Solutions Based on Phage Display-Based Antibody Development Platform

Creative Biolabs can provide phage display derived monoclonal antibodies and recombinant antibodies development solutions for researchers. We provide different types of analyses to evaluate antibodies after synthesis according to strict requirements.

Creative Biolabs has established many powerful technology platforms, such as phage display-based antibody development platforms. We have in-depth knowledge and experience of the tools and processes involved in the phage projects. Our skilled and dedicated scientific researchers ensure that the most suitable methods and techniques are selected for your project. If necessary, please feel free to contact us.

Please kindly note that our services can only be used to support research purposes (Not for clinical use).

Biophage Technology

Creative Biolabs is a globally recognized phage company. Creative Biolabs is committed to providing researchers with the most reliable service and the most competitive price.

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